Peters-Strickland T, Hatch A, Adenwala A, Atkinson K, Bartfeld B
Neuropsychiatr Dis Treat. 14:553-565. doi: 10.2147/NDT.S157102. eCollection 2018.
The digital medicine system (DMS), a drug-device combination developed for patients with serious mental illness, integrates adherence measurement with pharmacologic treatment by embedding an ingestible sensor in a pill, allowing for information sharing among patients, health care providers (HCPs), and caregivers via a mobile interface. Studies conducted during the DMS development process aimed to minimize cognitive burden and use-related risks and demonstrated effective use of the technology.