Shiffman S, Battista DR, Kelly JP, Malone MK, Weinstein RB, Kaufman DW
Br J Clin Pharmacol. doi: 10.1111/bcp.13551.
Aims to estimate prevalence of excess intake of acetaminophen, and investigate seasonal variations therein. Between 2011 and 2016, 14,481 US adults who used acetaminophen in the preceding 30 days were sampled from national online panels and completed a detailed online daily diary of acetaminophen medication use for 7 days. Respondents were not told the study concerned acetaminophen. Cold/flu season (CFS), identified using Google© Trends data, was contrasted to off-season in symptoms, use of acetaminophen medications, and consumption exceeding 4 grams (the recommended daily maximum).