Erik C. Nook, David Dodell-Feder, Laura T. Germine, Jill M. Hooley, Lynn E. DeLisi, Christine I. Hooker
Clinical,Volume 18,2018,Pages 40-50,ISSN 2213-1582.
2018-01-01
https://www.sciencedirect.com/science/article/pii/S2213158218300044
Understanding the specific mechanisms that explain why people who have relatives with schizophrenia (i.e., people at familial high risk; FHR) are more likely to develop the disorder is crucial for prevention. We investigated a diathesis-stress model of familial risk by testing whether FHR individuals under-recruit brain regions central to emotion regulation when exposed to social conflict, resulting in worse mood and symptoms following conflict.